George P. Allen, Pharm.D.
Chair and Associate Professor
Location
Dr. George Allen是药学院药学实践系的副教授和系主任, Westbrook College of Health Professions at the University of New England. Dr. Allen于1998年获得Massachusetts College of Pharmacy and Allied Health Sciences的药学博士学位. Dr. 随后，艾伦在西雅图的华盛顿大学完成了药学实习, WA, 并在底特律韦恩州立大学获得传染病药物治疗奖学金, MI. As a postdoctoral fellow, Dr. 艾伦进行了以实验室为基础的研究，检查了各种抗菌剂对细菌耐药性的诱导. Before joining the University of New England in 2010, Dr. 艾伦是波特兰俄勒冈州立大学药学院的一名教员, OR, 在那里他继续他的研究，并参与了药理学博士学生的教学和体验式教育.
Credentials
Education
Post-Doctoral Training
韦恩州立大学药学与联合健康学院(密歇根州底特律)
Residency, Pharmacy Practice
University of Washington and Harborview Medical Centers (Seattle, Washington)
Research
Current research
Dr. 艾伦的研究重点是抗菌素耐药性的药效学研究. 他使用体外建模技术，可以评估不同抗菌素暴露对耐药性发展的影响. The majority of Dr. 艾伦目前的工作包括研究两种独特的抗菌活性措施, the mutant prevention concentration and mutant selection window. 这项工作是使用多种临床重要的细菌物种进行的，包括 Neisseria gonorrhoeae, Klebsiella pneumoniae, Salmonella enterica, and Shigella flexneri, with most research focusing on the fluoroquinolone antimicrobials. Broadly speaking, Dr. Allen的工作旨在确定哪些抗菌剂(以及所述抗菌剂的最佳剂量)可以在实验室和实验室中最好地防止细菌耐药性的出现, potentially, in clinical settings.
Selected publications
Allen GP, Deao KM, Hill SA, Schipelliti SM, Tran T. In vitro evaluation of antimicrobial resistance selection in Neisseria gonorrhoeae. International Journal of Antimicrobial Agents 2021;58:106417.
Allen GP, Harris KA. In vitro resistance selection in Shigella flexneri by azithromycin, ceftriaxone, ciprofloxacin, levofloxacin, and moxifloxacin. Antimicrobial Agents and Chemotherapy 2017;61:e00082-17.
Allen GP, Moore WM, Moser LR, Neill KK, Sambamoorthi U, Bell HS. 服务型领导和变革型领导在学术药学中的作用. American Journal of Pharmaceutical Education 2016;80:Article 113.
McGregor JC, Hartung DM, Allen GP, Taplitz RA, Traver R, Tong T, Bearden DT. Risk factors associated with linezolid non-susceptible enterococcal infections. American Journal of Infection Control 2012;40:886-7.
Allen GP, Deshpande LM. Determination of the mutant selection window for clindamycin, doxycycline, linezolid, moxifloxacin, 甲氧苄啶/磺胺甲恶唑治疗社区相关的甲氧西林耐药 Staphylococcus aureus. International Journal of Antimicrobial Agents 2010;35:45-9.
Allen GP, Hankins CD. Evaluation of the mutant selection window for fluoroquinolones against Neisseria gonorrhoeae. Journal of Antimicrobial Chemotherapy 2009;64:359-63.
Allen GP, Bierman BC. 利奈唑胺对万古霉素敏感和耐药的体外耐药选择分析 Enterococcus faecalis and Enterococcus faecium. International Journal of Antimicrobial Agents 2009;34:21-4.
McGregor JC, Allen GP, Bearden DT. 左氧氟沙星治疗并发尿路感染及急性肾盂肾炎. Therapeutics and Clinical Risk Management 2008;4:843-53.
Bearden DT, Allen GP, Christensen JM. 局部伤口护理产品对社区相关的甲氧西林耐药的体外活性比较 Staphylococcus aureus. Journal of Antimicrobial Chemotherapy 2008;62:769-72.
Allen GP, Kaatz GW, Rybak MJ. 靶向浓度氟喹诺酮类药物抗突变体的体外活性研究 Staphylococcus aureus in a pharmacodynamic model. International Journal of Antimicrobial Agents 2004;24:150-60.
Bearden DT, Allen GP. 抗菌药物控制项目对患者结果的影响:药学角度. Disease Management and Health Outcomes 2003;11:723-36.
Allen GP, Kaatz GW, Rybak MJ. 突变体预防浓度靶向莫西沙星和左氧氟沙星抗 Streptococcus pneumoniae in an in vitro pharmacodynamic model. Antimicrobial Agents and Chemotherapy 2003;47:2606-14.
Allen GP. The mutant prevention concentration: a review. Journal of Infectious Diseases Pharmacotherapy 2003;6:27-47.
Allen GP, Cha RC, Rybak MJ. In vitro activities of quinupristin-dalfopristin and cefepime, 在体外药效学模型中单独或与多种抗菌素联合治疗多重耐药葡萄球菌和肠球菌. Antimicrobial Agents and Chemotherapy 2002;46:2606-12.
Other scholarly activity
Springer SP, Allen GP. Utilizing virtual reality to introduce hospice and end-of-life approaches. American Association of Colleges of Pharmacy Annual Meeting, July 2021. [Virtual]
Vincent S, Mayer R, Allen G, Dornblaser E. 在药学院的变革中为幸福创造机会. American Association of Colleges of Pharmacy Annual Meeting, July 2021. [Virtual]
Allen GP, Brooks L, Deao KM, Gosling K, Hill SA. In vitro evaluation of resistance selection in Shigella sonnei by ceftriaxone, ertapenem, ciprofloxacin, levofloxacin, and moxifloxacin. Abstract 5715. 美国微生物学会和欧洲微生物学会联合会第一届世界微生物论坛, June 2021. [Virtual]
Gosling K, Brooks L, Deao KM, Hill SA, Allen GP. Evaluation of in vitro fluoroquinolone resistance selection in Shigella sonnei. Abstract SP-654. 55th American Society of Health-System Pharmacists Midyear Clinical Meeting, New Orleans, LA, December 2020. [Virtual]
Tran T, Deao KM, Hill SA, Schipelliti SM, Allen GP. Evaluation of in vitro mutant selection in Neisseria gonorrhoeae by azithromycin, ceftriaxone, doxycycline, ertapenem, gentamicin, ciprofloxacin, levofloxacin, and moxifloxacin. Abstract SP-657. 55th American Society of Health-System Pharmacists Midyear Clinical Meeting, New Orleans, LA, December 2020. [Virtual]
Greenleaf T, Barlow D, Rieder C, Allen G, May M, Houseknecht K. Examining bacterial resistance using varied experimental approaches. Abstract 15. 正规澳门赌场网络骨科医学院学生研究和奖学金论坛, Biddeford, ME, September 2018. [Encore Presentation]
Greenleaf T, Barlow D, Rieder C, Allen G, May M, Houseknecht K. Examining bacterial resistance using varied experimental approaches. MDI生物实验室夏季学生研讨会，酒吧港，缅因州，2018年8月.
Brazeau D, Lobaina E, Nguyen H, Ciapciak K, Carlson A, Allen G, Karamchi M. 评估粪便拭子收集和运输系统在长时间储存后肠道病原体的DNA恢复. Abstract P0430. 第28届欧洲临床微生物学和传染病大会，西班牙马德里，2018年4月.
Black C, Harris KA, Allen GP. Evaluation of in vitro resistance selection in Shigella flexneri by chloramphenicol, gemifloxacin, levofloxacin, pivmecillinam, and rifaximin. Maine Pharmacy Association Sesquicentennial, Portland, ME, October 2017. [Encore Presentation and Award: Best Poster]
Allen GP, Black C, Harris KA. Evaluation of in vitro resistance selection in Shigella flexneri by chloramphenicol, gemifloxacin, levofloxacin, pivmecillinam, and rifaximin. Abstract FRIDAY-96. ASM Microbe 2017, New Orleans, LA, June 2017.
Brazeau D, Kim W, Kollar R, Allen G, Vaughn J. 评价RNA保存缓冲液在临床和野外样品中储存高质量RNA的效果. Abstract SATURDAY-502. ASM Microbe 2017, New Orleans, LA, June 2017.
Brazeau D, Karamchi M, Kollar R, Kim W, Allen G, Vaughn J. 一种液体胺基培养基在物种特异性Q-PCR检测病毒和细菌病原体中的性能评价. Abstract TUESDAY-63. ASM Clinical Virology Symposium, Savannah, GA, May 2017.
Allen GP, Harris KA. In vitro evaluation of resistance selection in Shigella flexneri by azithromycin, ceftriaxone, ciprofloxacin, levofloxacin, and moxifloxacin. Abstract SUNDAY-513. ASM Microbe 2016, Boston, MA, June 2016.
Allen GP, Lee JK, Tsui AY, Vo TN. In vitro evaluation of resistance selection by various antimicrobials in Escherichia coli. Abstract A-482. 第55届抗菌药物和化疗科学会议，2015年9月，加州阿纳海姆.
Allen GP, Eastman KS, Freudenberger KR. Evaluation of in vitro resistance selection in Shigella flexneri by azithromycin, ceftriaxone, and ciprofloxacin. Abstract A-483. 第55届抗菌药物和化疗科学会议，2015年9月，加州阿纳海姆.
Brazeau D, Karamchi M, Kim WE, Allen GP. Performance evaluation of Puritan© Opti-Tranz medium in detection of Bordetella pertussis using real time Q-PCR. Abstract 1087. 美国微生物学会第115届大会，新奥尔良，洛杉矶，2015年5 - 6月.
Allen GP, Astrup GE, Dizon JM, McIver LA, Park DY. 抗氟喹诺酮类药物耐药性联合抗菌药物的体外评价 Neisseria gonorrhoeae. Abstract A-1331. 54th Interscience Conference on Antimicrobial Agents and Chemotherapy, Washington, DC, September 2014.
Allen GP, Teklemariam KT, Ton-Nu PD. In vitro evaluation of azithromycin, ceftriaxone, chloramphenicol, ciprofloxacin, ertapenem, fosfomycin, and moxifloxacin against Salmonella enterica serovar Typhi. 4th American Society for Microbiology Conference on Salmonella: The Bacterium, the Host and the Environment, Boston, MA, October 2013.
Allen GP, Paplaskas AM, Malinowski A. In vitro evaluation of antimicrobial combinations against NDM-1 producing Klebsiella pneumoniae. Abstract A-1038. 第53届抗菌药物与化疗科学会议，丹佛，2013年9月.
Allen GP, Paplaskas AM, Malinowski A. 多粘菌素和多粘菌素B与多种抗碳青霉烯酶产生的抗菌剂联合应用的体外评价 Klebsiella pneumoniae (KPC). Abstract 18. 1st International Conference on Polymyxins, Prato, Italy, May 2013.
Allen GP, Paplaskas AM, Malinowski A. In vitro evaluation of colistin and polymyxin B, alone and in combination with doxycycline, fosfomycin, and tigecycline, against carbapenemase-producing Klebsiella pneumoniae. Abstract B14. 新英格兰生物防御和新发传染病卓越区域中心(NERCE/BEID)第8届年会, Newport, RI, November 2012.
Allen GP, Ofodile CC. Evaluation of azithromycin (AZM), ceftriaxone (CRO), and fluoroquinolone (FQ) resistance selection in Salmonella Choleraesuis (SC), S. Paratyphi (SP), and S. Typhimurium (ST). Abstract 126C. 第三届美国微生物学会人畜共患细菌和食源性病原体抗菌素耐药性会议, Aix-en-Provence, France, June 2012.
Allen GP, Lakoma LD, Malinowski A. 阿奇霉素(AZM)与克拉霉素(CLR)耐药性选择的比较评价 Salmonella Typhi (ST) using an in vitro pharmacodynamic model (IVPM). Abstract A-037. 第51届抗菌药物与化疗科学会议，芝加哥，伊利诺伊州，2011年9月.
Research interests
Antimicrobial pharmacodynamics, Antimicrobial resistance